Abstract

Introduction: Metabolic syndrome is a growing public health concern around the world and there is an urgent need to control it by using the methods with minimal side effects. Therefore, this study was performed with aim to evaluate the effect of cuminum cyminum on metabolic syndrome indicators. Methods: This three-blind clinical trial study was performed in 2019 on 66 women of reproductive age who had at least three metabolic syndrome indicators and referred to the comprehensive health service centers of Rafsanjan city. The subjects were selected by convenience and randomly assigned to the two groups of receiving 500 mg of cuminum cyminum and placebo. Before and after 8 weeks of the intervention, waist circumference, FBS, HDL, and triglyceride were measured. Data were analyzed by SPSS software (version 18) and Kolmogorov-Smirnov, independent t-test, Mann-Whitney U, paired t-test and Wilcoxon tests. P<0.05 was considered statistically significant. Results: The mean of waist circumference, TG, HDL, and systolic blood pressure before and after the intervention had significant difference in the cuminum cyminum group (P<0.05). These changes were not significant in the control group. The mean of FBS did not significantly change in the cumin group)P=0.739), but in the control group, the FBS level increased (p=0.004). The mean of diastolic blood pressure in both groups significantly decreased after the intervention (p<0.05), but the decrease was more in the cumin group (p<0.001). Conclusion: Consumption of 500 mg of cuminum cyminum twice a day can improve the indicators of metabolic syndrome in women of reproductive age.