(2016) The Role of Interleukin-17A (IL-17A) in Depression. Iranian Red Crescent Medical Journal. p. 4. ISSN 2074-1804
Full text not available from this repository.
Abstract
Context: The aim of this review was to address the recent data regarding the role of IL-17A in the pathogenesis of depression and its complications, such as cancer. Evidence Acquisition: This review article summarizes the recent data on the role of IL-17A in depression, using the PubMed and Google Scholar databases. Results: It has been documented that depression may alter the immune response via unknown mechanism/s. It is possible that immune responses and depression are linked via several molecules, including cytokines. IL-17A, a pro-inflammatory cytokine, participates in the pathogenesis of several inflammatory-based diseases, such as autoimmunity. Conclusions: Due to the comorbidity of depression and chronic inflammatory processes, and depression's effect on the immune system, it may be hypothesized that the IL-17A cytokine plays a key role in the pathogenesis of depression.
Item Type: | Article |
---|---|
Keywords: | Depression IL-17A Th17 th17 cells hepatocellular-carcinoma antidepressant treatment rheumatoid-arthritis tumor progression plasma-levels cytokines infection differentiation inflammation General & Internal Medicine |
Page Range: | p. 4 |
Journal or Publication Title: | Iranian Red Crescent Medical Journal |
Journal Index: | ISI |
Volume: | 18 |
Number: | 12 |
Identification Number: | https://doi.org/10.5812/ircmj.24972 |
ISSN: | 2074-1804 |
Depositing User: | مهندس مهدی شریفی |
URI: | http://eprints.rums.ac.ir/id/eprint/4444 |
Actions (login required)
![]() |
View Item |