Repository of Research and Investigative Information

Repository of Research and Investigative Information

Rafsanjan University of Medical Sciences

High Serum Levels of TGF-beta in Iranians With Chronic HBV Infection

(2012) High Serum Levels of TGF-beta in Iranians With Chronic HBV Infection. Hepatitis Monthly. p. 4. ISSN 1735-143X

[img] Text
70451-pdf.pdf

Download (452kB)

Official URL: http://apps.webofknowledge.com/InboundService.do?F...

Abstract

Background: The transforming growth factor-beta (TGF-beta) is an important cytokine with anti-inflammatory properties. Objectives: The main purpose of this study was to compare the serum levels of TGF-beta in a group of chronic HBV infected (CHB) patients as well as healthy individuals from South-East of Iran. Patients and Methods: Sixty patients with CHB as well as sixty healthy individuals were enrolled in the study. ELISA technique was applied to measure the serum levels of TGF-beta in both groups. Results: Our results revealed that the serum levels of TGF-beta were significantly increased in CHB patients in compare to healthy controls. Conclusions: According to this result, it may be concluded that high serum levels of TGF-beta may be a mechanism by which immune response against HBV is suppressed. Published by Kowsar Corp, 2012. cc 3.0.

Item Type: Article
Keywords: Hepatitis B, Chronic Transforming Growth Factor Beta chronic hepatitis-b virus-infection liver controversies polymorphism receptor il-10 cells gene Gastroenterology & Hepatology
Page Range: p. 4
Journal or Publication Title: Hepatitis Monthly
Journal Index: ISI
Volume: 12
Number: 11
Identification Number: https://doi.org/10.5812/hepatmon.7581
ISSN: 1735-143X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.rums.ac.ir/id/eprint/4749

Actions (login required)

View Item View Item