Repository of Research and Investigative Information

Repository of Research and Investigative Information

Rafsanjan University of Medical Sciences

Cytokines in Preterm Delivery

(2012) Cytokines in Preterm Delivery. Labmedicine. pp. 129-131. ISSN 0007-5027

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Abstract

Background: This study aimed to investigate the serum levels of interleukin-12 (IL-12), interleukin-10 (IL-10), and interleukin-6 (IL-6) in preterm neonates and their mothers and to compare them with those of full-term neonates and their mothers. Materials and Methods: One hundred cord blood specimens from full-term neonates and 60 from preterm neonates were collected. Likewise, 100 plasma samples from the mothers of the full-term neonates and 60 from the mothers of the preterm neonates were collected. Serum levels of IL-12, IL-10, and IL-6 were measured by enzyme-linked immunosorbent assay (ELISA). Results: Cord blood levels of IL-12 and serum levels of IL-6 were higher in preterm neonates and their mothers, respectively. Conclusion: Based on these findings, serum levels of IL-6 and IL-12 may be associated with preterm delivery. More studies must be completed to confirm the key role of these cytokines for the prognosis of preterm labor.

Item Type: Article
Keywords: IL-6 IL-12 IL-10 pregnancy preterm delivery Medical Laboratory Technology
Page Range: pp. 129-131
Journal or Publication Title: Labmedicine
Journal Index: ISI
Volume: 43
Number: 4
Identification Number: https://doi.org/10.1309/lm9ilgsetu2coo
ISSN: 0007-5027
Depositing User: مهندس مهدی شریفی
URI: http://eprints.rums.ac.ir/id/eprint/4771

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