Repository of Research and Investigative Information

Repository of Research and Investigative Information

Rafsanjan University of Medical Sciences

Common HBV Genotype in Southeastern Iranian Patients

(2010) Common HBV Genotype in Southeastern Iranian Patients. Archives of Iranian Medicine. pp. 147-149. ISSN 1029-2977

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Asymptomatic hepatitis B infection is characterized as a type of hepatitis in which hepatitis B surface antigen is present in the patient's peripheral blood despite the absence of clinical symptoms. Previous studies have shown that a particular genotype may effect clinical manifestations of hepatitis B infection; hence, the aim of the current study was to determine the frequency of hepatitis B virus genotypes among asymptomatic carriers of hepatitis B. In this experimental study, the plasma samples of 100 asymptomatic carriers were collected and tested for HBsAg and anti-HBs using ELISA. The genotype of hepatitis B virus was determined by the GAP-PCR technique. The results of this study showed that all samples were positive for hepatitis B surface antigen and anti-hepatitis B core antigen was present in 60 (60) cases. Our results also indicated that all patients had the D genotype of hepatitis B virus.

Item Type: Article
Keywords: Asymptomatic hepatitis B infection genotype hepatitis B surface antigen hepatitis B virus DNA polymorphism hepatitis-b-virus General & Internal Medicine
Page Range: pp. 147-149
Journal or Publication Title: Archives of Iranian Medicine
Journal Index: ISI
Volume: 13
Number: 2
ISSN: 1029-2977
Depositing User: مهندس مهدی شریفی

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