Repository of Research and Investigative Information

Repository of Research and Investigative Information

Rafsanjan University of Medical Sciences

A survey on stimulatory effects of topical application of radioactive lantern mantle powder on wound healing

(2008) A survey on stimulatory effects of topical application of radioactive lantern mantle powder on wound healing. Iranian Journal of Radiation Research. pp. 101-106. ISSN 1728-4554

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Abstract

Background: Poorly educated people in some parts of Iran use burned mantles as a wound healing medicine. Materials and Methods: To perform surface area measurement, twenty rats were divided randomly into two groups of 10 animals each. The first group received topical burned radioactive lantern mantle powder on the first to third days after making excision wounds. The second group received non-radioactive lantern mantle powder. For histological study, 36 male rats were randomly divided into two groups of 18 animals each. Full thickness excision wound (314 +/- 31.4 mm(2)) was made on the dorsal neck in all animals after inducing general anesthesia. For the first three days, cases had received topical application of the radioactive lantern mantle powder. Finally, to measure the tensile strength, an incision was made on the dorsal neck of the rats. Results: Surface area measurement of the wounds showed a progressive surface reduction in both groups. Histological study showed a significant statistically difference between cases and controls with respect to fibrinoid necrosis and neutrophilic exudate on days 3 and 14. Considering the existence of granulated tissue, a significant difference was observed between case and control groups on days 3 and 7. Tensile strength study showed no significant difference between the cases and controls. Conclusion: Topical use of radioactive mantle powder can accelerate the healing process of the wound in rats. Iran. J. Radiat Res., 2008; 6 (2): 101-106

Item Type: Article
Keywords: Lantern mantle wound healing radioactive thorium cytogenetic adaptive response low-dose radiation human-lymphocytes x-rays ionizing-radiation cells induction variability irradiation thymidine Radiology, Nuclear Medicine & Medical Imaging
Page Range: pp. 101-106
Journal or Publication Title: Iranian Journal of Radiation Research
Journal Index: ISI
Volume: 6
Number: 2
ISSN: 1728-4554
Depositing User: مهندس مهدی شریفی
URI: http://eprints.rums.ac.ir/id/eprint/4906

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