Repository of Research and Investigative Information

Repository of Research and Investigative Information

Rafsanjan University of Medical Sciences

Evaluation of meloxicam (a Cox-2 inhibitor) for management of postoperative endodontic pain: A double-blind placebo-controlled study

(2003) Evaluation of meloxicam (a Cox-2 inhibitor) for management of postoperative endodontic pain: A double-blind placebo-controlled study. Journal of Endodontics. pp. 634-637. ISSN 0099-2399

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Abstract

Successful management of endodontic pain represents a continuing challenge. The purpose of this randomized, double-blind, placebo-controlled, parallel-group trial was to compare the pain reducing effect of oral preparations of meloxicam, piroxicam, and placebo in endodontic emergency patients. A total of 51 patients who presented to the Tehran University endodontic clinic and one private dental clinic were invited to participate. Patients were asked to evaluate their pretreatment pain with a visual-analog scale. After root canal therapy they were randomly assigned to one of three groups: meloxicam, piroxicam, or placebo. Each patient was sent home with a visual-analog scale to fill out at 8 and 24 h after completion of therapy. The results of this study showed no significant differences between efficacy of meloxicam, piroxicam, and placebo, but a significant effect of the time factor in reducing postoperative pain in all treatment groups was observed.

Item Type: Article
Keywords: nonsteroidal antiinflammatory drugs ketorolac tromethamine intracanal use tolerability piroxicam efficacy osteoarthritis medications therapy safety Dentistry, Oral Surgery & Medicine
Page Range: pp. 634-637
Journal or Publication Title: Journal of Endodontics
Journal Index: ISI
Volume: 29
Number: 10
Identification Number: https://doi.org/10.1097/00004770-200310000-00005
ISSN: 0099-2399
Depositing User: مهندس مهدی شریفی
URI: http://eprints.rums.ac.ir/id/eprint/4940

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